Services
Services available at the Biotechnology Development Unit
development
processing
processing
chemistry
of biologics
Services available at the Biotechnology Development Unit
Cell line
development
High-throughput screening of mammalian cell line using Clonepix2 technology.
Upstream
processing
4 x 250 ml parallel single use bioreactors and 2 l biorector for mammalian cells, 2 x 2 l parallel bioreactors and 30 l bioreactor for microbs.
Downstream
processing
Expertise in all kind of chromatography for lab to industrial-scale purification of biologics.
Linkers
chemistry
PEGs and fatty acids polymers preparation and conjugation.
Quality Control
of biologics
RP-HPLC, IEF, WB, SDS-PAGE, related proteins, dimmers and oligomers detection, impurities detection (HCP, endotoxins, residual DNA), peptide mapping, flow cytometry, in vitro and in vivo bioactivity, protein identification and mapping by LC-MSMS, oligonucleotide QC by LC-MSMS, small molecule quantification by LC-MSMS, CZE, glycan analysis, HPLC-UV-ELSD analysis)